What is Acyclovir? Antiviral drug acyclovir is one of them. It stops the herpes virus from multiplying and spreading in the body. It won't get rid of herpes, but it will assist with the symptoms. Acyclovir is used to treat herpes virus diseases like genital herpes, cold sores, shingles, and chickenpox. Acyclovir is also used to treat genital herpes outbreaks and reduce outbreak frequency, limit...